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Table 8 Comparison among the perfusion parameters and MVD between VEGF positive and negative expression of three groups of peripheral pulmonary nodules

From: Peripheral pulmonary nodules: Relationship between multi-slice spiral CT perfusion imaging and tumor angiogenesis and VEGF expression

Pulmonary nodule

Parameter

BV

BF

MTT

PS

PH

PHpm/PHa (100%)

MVD

Peripheral lung cancer

VEGF positive expression (n = 29)

11.457 ± 3.593

225.406 ± 83.556

7.326 ± 3.807

21.638 ± 7.050

62.531 ± 8.579

21.285 ± 3.238

32.495 ± 14.541

 

VEGF negative expression (n = 10)

8.025 ± 2.859

146.728 ± 88.744

7.896 ± 3.787

14.090 ± 6.785

55.740 ± 5.132

18.657 ± 2.466

20.002 ± 9.363

 

F

7.449

6.394

0.167

8.680

5.522

5.455

6.400

 

P

0.010

0.016

0.685

0.006

0.024

0.025

0.016

Inflammatory nodule

VEGF positive expression (n = 0)

/

/

/

/

/

/

/

 

VEGF negative expression (n = 13)

8.542 ± 2.581

160.902 ± 68.412

6.397 ± 3.292

4.019 ± 1.730

65.700 ± 5.948

22.163 ± 2.240

33.966 ± 15.548

Benign nodule

VEGF positive expression (n = 3)

6.620 ± 2.231

83.070 ± 25.153

6.320 ± 1.890

5.047 ± 2.945

30.733 ± 14.199

9.793 ± 4.177

8.877 ± 3.285

 

VEGF negative expression (n = 9)

5.534 ± 1.439

79.954 ± 13.919

5.573 ± 3.222

3.380 ± 1.903

26.867 ± 7.652

8.592 ± 2.168

7.653 ± 2.081

 

F

1.000

0.078

0.139

1.350

0.386

0.448

0.599

 

P

0.341

0.786

0.717

0.272

0.548

0.519

0.457

  1. *Data is the mean ± SD.