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Figure 1 | BMC Cancer

Figure 1

From: Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors

Figure 1

Expression of syndecan-1 in normal colonic epithelium and colon adenocarcinomas. a, immunohistochemical staining for syndecan-1 in normal colon. b-c, syndecan-1 staining of colon adenocarcinomas is lost in correlation with tumor differentiation status. d, example of a moderately differentiated adenocarcinoma with strong stromal staining for syndecan-1 and moderate staining of the tumor. e, f, contiguous sections of the same tumor stained for syndecan-1, (e), or fascin, (f), demonstrating strong staining for fascin in the stroma (arrowed). The tumor cells are negative for fascin and syndecan-1. Isolated strongly fascin positive cells correspond to dendritic and vascular endothelial cells and provideinternal positive controls for the fascin staining.

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