Table 1 Individual tumor characteristics, mutation, and CGH analyses
From: Recurrent and multiple bladder tumors show conserved expression profiles
Tumor1 | mtr2 | Stage/grade3 | FGFR3mut4,5 | TP53mut4 | Imbalances6 |
|---|---|---|---|---|---|
01.I | TaG2 | dim (8p., 22p, 22q11–13.1) | |||
enh (8q11–q22, Xq) | |||||
01.R1 | 5 | TaG2 | dim (8p) | ||
enh (8q) | |||||
02.I | T2G3 | dim (19p) | |||
enh (1p31–p32, 1q23–q25, 8q, 12q13–q21) | |||||
02.R1 | 7 | T2G3 | enh (1q23–q24, 2p14-pter, 3p22-pter) | ||
07.I | TaG1 | S249C | na | ||
07.R1 | 7 | TaG2 | S249C | K132N | na |
09.I | T1G3 | G245D | dim (2q33-qter, 6q24-qter, 9, 10q, 11p15-pter, 17, 22) | ||
enh (1p11–p21, 1q11–q31, 2q11, 2q23–q24, 3, 8q11–q22, 11q14-qter, 16p, 16q11–q13, 18p, 20, X) | |||||
09.R1 | 10 | TIG3 | G245D | dim (9) | |
enh (1q22–q31, 2p13-pter, 3, 8, 16p, 16q11–q13, 20) | |||||
10.I | T1G2 | S249C | R280T | dim (9q) | |
enh (12q13–q21) | |||||
10.R1 | 5 | T1G3 | S249C | R280T | dim (9q22-qter, 10q24-qter) |
enh (10q21–q23, 20q, Xp, Xq11–q24) | |||||
13.I | T1G2 | dim (9q, 10p12–p13, 16p, 17p, 19, 22) | |||
enh (1p11–p31, 1q11–q41, 3, 5q14–q23, 8q13-qter, 12q15–q22, 13, 18q, 20p, X) | |||||
13.R1 | 6 | T0 | dim (4, 9, 17p, 19) | ||
enh (1q23-qter, 3, 5q13–q23, 13, 14, 17q, 18q, 20, X) | |||||
14.I | T1G2 | dim (8p, 9, 10p, 17p) | |||
enh (8q) | |||||
14.R1 | 8 | T1G3 | dim (9, 10p, 19) | ||
enh (8q) | |||||
16.I | TIG3 | dim (8q) | |||
enh (8p, 19) | |||||
16.R1 | 4 | T1G2 | dim (8q) | ||
18.I | T1G2 | dim (8p) | |||
enh (1p32-pter, 1p13–p21, 1q21–q31, 1q33–q35, 3, 5p, 6p11–p22, 8q21-qter, 10q11–q23, 13q22-qter) | |||||
18.R1 | 16 | T2G3 | R273L | enh (3, 8q11–q23, 9p) | |
21.I | TaG2 | dim (9q22-qter, 11p13-qter, 22) | |||
enh (12p11–p12, 12q11–q23) | |||||
21.R1 | 7 | T1G2 | dim (8p, 9q, 10p, 11p, 11q11–q13.1, 12q24-qter, 16p, 17, 18p, 19, 22) | ||
enh (3, 4p11–p15, 4q11–q32, 5q21–q23, 6q11–q14, 8q, 12q15–q21, 13q14-qter, 18q11–q22) | |||||
29.I | TaG2 | S249C | dim (9q32-qter, 14q23-qter, 19) | ||
enh (1q22-qter, 8q) | |||||
29.R1 | 21 | TaG2 | S249C | dim (9q22-qter) | |
enh (1q11–q31, 13, X) | |||||
30.I | TaG2 | na | |||
30.R1 | 13 | TaG2 | na | ||
31.I | TaG2 | R290H | na | ||
31.R1 | 10 | TaG2 | na | ||
31.R2 | 17 | TaG2 | dim (2q34-qter, 8p, 14, 19p) | ||
enh (1q21-qter, 2p13-pter, 5p13-pter, 8q, 11q14–q24) | |||||
31.R3 | 19 | T4G3 | dim (2q31–q34, 5q11–q23, 6q, 9p12-pter) | ||
enh (1q23–q24, 1q32-qter, 2p, 2q11–q14, 5p, 8) | |||||
34.I | T1G3 | S249C | dim (9, 11p11-pter, 12p) | ||
enh (1p31–p32, 1q23–q41) | |||||
34.R1 | 6 | T2G3 | S249C | dim (8p, 9) | |
enh (8q) | |||||
38.I | T1G3 | R248Q | dim (9) | ||
38.R1 | 9 | T2G3 | R248Q | na | |
38.R2 | 24 | T2G3 | R248Q | dim (19p) | |
enh (2q14–q21, 8q22-qter) | |||||
42.I | TaG2 | S249C | dim (5q, 10q11–q21, 10q23-qter, 13p, 13q11–q14, 15, 17p, 18q, 19p) | ||
enh (2p13-pter, 3, 5p, 6p22-pter, 8q13-qter, 9p22.1-pter, 12q14–q21.2, 18p, X) | |||||
42.R1 | 31 | TaG1 | S249C | enh (1q24-qter, 8q21–q23) | |
43.I | TaG1 | S249C | na | ||
43.R1 | 4 | TaG1 | Y375C | na | |
47.I | TaG2 | na | |||
47.R1 | 5 | TaG2 | na | ||
47.R2 | 18 | TaG1 | na | ||
53.I | TaG2 | S249C | enh (X) | ||
53.R1.S1 | 27 | T1G2 | S249C | dim (19p) | |
53.R1.S2 | 27 | T1G2 | S249C | dim (19p) | |
enh (Xp11-pter, Xq26-qter) | |||||
54.S1 | - | T1G3 | enh (1q23) | ||
54.S2 | - | T1G3 | enh (8q21-qter, 12, 13) | ||
56.S1 | - | T2G3 | dim (2q32.2-qter, 5q, 15, 16q) | ||
enh (1p, 1q12–q23, 3, 5p, 8q, 13q21-qter, 16p, 17q, 20, 21, Xp22-pter) | |||||
56.S2 | - | T2G3 | Q331STOP | dim (8p) | |
enh (1, 2p, 2q11–q21, 3, 5p, 6p12-pter, 6q21–q23, 7p, 7q32-qter, 8q, 10p, 15q21-qter, 20) | |||||
64.S1 | - | T3G3 | na | na | na |
64.S2 | - | T3G3 | na | na | na |