Figure 7
From: ELR+ CXC chemokine expression in benign and malignant colorectal conditions
Detection of CXCL5 protein expression in representative CRA, CRC and CRLM specimens as assessed by immunohistochemical staining with CXCL5 -specific antibodies. (A) Weak cytoplasmic signals in basal crypt cells within tumor neighbor tissues of CRA, (B) very weak immunostaining in CRA specimens, (C) weak insular epithelial signals in tumor neighbor tissues of CRC, (D) intense basal and apical epithelial signals and interspersed rare mesenchymal signals in CRC tissues, (E) no substantial reactivity in corresponding neighbour tissues of CRLM and (F) intensive staining signals in epithelial and mesenchymal cells within tumor areas of CRLM specimens (original magnification 200 and 400 fold, respectively).