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Table 5 Fisher's exact test between RXRs nuclear expression and different clinicopathological data of the patients presenting infiltrative carcinomas.

From: Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

  

RXR-α N

RXR-β N

RXR-γ N

  

Negative

Positive

p-value

Negative

Positive

p-value

Negative

Positive

p-value

Tumor Type

Ductal

31

23

0.819

46

8

0.503

46

8

0.406

 

Lobular

12

10

 

20

2

 

17

5

 

Age

<50

9

10

0.391

17

2

0.713

17

2

0.394

 

>50

34

24

 

50

8

 

47

11

 

Tumor size

1

21

10

0.304

27

4

0.829

26

5

0.123

 

2

17

16

 

28

5

 

30

3

 
 

3

2

3

 

5

0

 

3

2

 
 

4

3

5

 

7

1

 

5

3

 

Nodal status

-

19

16

0.802

28

7

0.095

28

7

0.505

 

+

24

18

 

39

3

 

36

6

 

ER

0

8

9

0.093

15

2

0.254

16

1

0.116

 

1

1

5

 

6

0

 

6

0

 
 

2

6

6

 

12

0

 

11

1

 
 

3

28

14

 

34

8

 

31

11

 

PR

0

13

8

0.010

18

3

0.608

17

4

0.641

 

1

0

7

 

7

0

 

7

0

 
 

2

6

7

 

12

1

 

11

2

 
 

3

24

12

 

30

6

 

29

7

 
  1. Tumor size (TNM): T = 1, 2, 3, 4. ER and PR: 0 = Negative, 1 = Weak immunoreaction, 2/3 = High immunoreaction. N: nuclear immunoreaction.
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