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Table 3 Fisher's exact test between hPXR expression and different clinicopathological data of the patients presenting infiltrative carcinomas.

From: Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

   

hPXR1.2 C

hPXR1.2 N

hPXR1 C

  

Total

Weak

High

p-value

Negative

Positive

p-value

Weak

High

p-value

Tumor Type

Ductal

54

26

28

0.613

39

15

0.002

33

21

0.374

 

Lobular

22

12

10

 

16

6

 

11

11

 

Age

<50

19

13

6

0.055

13

6

0.738

12

7

0.542

 

>50

58

25

33

 

42

16

 

32

26

 

Tumor size

1

31

20

11

0.083

27

4

0.077

23

8

0.088

 

2

33

15

18

 

21

12

 

16

17

 
 

3

5

1

4

 

3

2

 

2

3

 
 

4

8

2

6

 

4

4

 

3

5

 

Nodal status

-

35

20

15

0.212

30

5

0.011

21

14

0.644

 

+

42

18

24

 

25

17

 

23

19

 

ER

0

17

7

10

0.257

9

8

0.001

10

7

0.161

 

1

6

1

5

 

1

5

 

1

5

 
 

2

12

6

6

 

9

3

 

6

6

 
 

3

42

24

18

 

36

6

 

27

15

 

PR

0

21

10

11

0.031

14

7

0.000

12

9

0.004

 

1

7

0

7

 

0

7

 

0

7

 
 

2

13

6

7

 

10

3

 

6

7

 
 

3

36

22

14

 

31

5

 

26

10

 
  1. Tumor size (TNM): T = 1, 2, 3, 4. ER and PR: 0 = Negative, 1 = Weak immunoreaction, 2/3 = High immunoreaction. C: Cytoplasmic immunoreaction. N: nuclear immunoreaction.
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