BMC Cancer

Table 2 Fisher's exact test between the expression of the different isoforms of hPXR and that the retinoid receptors in infiltrative carcinomas.

From: Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

			hPXR1.2 C			hPXR1.2 N			hPXR1 C
		Total	Weak	High	p-value	Negative	Positive	p-value	Weak	High	p-value
RXR-α C	Negative	45	17	28	0.035	24	21	<0.001	19	26	0.007
	Weak	6	5	1		6	0		5	1
	High	26	16	10		25	1		20	6
	Total	77	38	39		55	22		44	33
RXR-α N	Negative	43	30	13	<0.001	42	1	<0.001	34	9	<0.001
	Positive	34	8	26		13	21		10	24
	Total	77	38	39		55	22		44	33
RXR-β C	Negative	35	18	17	0.021	22	13	0.045	18	17	0.329
	Weak	18	13	5		17	1		13	5
	High	24	7	17		16	8		13	11
	Total	77	38	39		55	22		44	33
RXR-β N	Negative	67	32	35	0.470	48	19	0.915	38	29	0.845
	Positive	10	6	4		7	3		6	4
	Total	77	38	39		55	22		44	33
RXR-γ C	Negative	32	21	11	0.001	28	4	0.001	24	8	<0.001
	Weak	12	9	3		11	1		10	2
	High	33	8	25		16	17		10	23
	Total	77	38	39		55	22		44	33
RXR-γ N	Negative	64	34	30	0.142	46	18	0.847	37	27	0.792
	Positive	13	4	9		9	4		7	6
	Total	77	38	39		55	22		44	33

C: Cytoplasmic immunoreaction. N: nuclear immunoreaction.

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ISSN: 1471-2407

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