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Table 3 Survival analysis of histopathologic prognostic factors in pancreatobiliary resections (n = 67)

From: Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma

   

p-value

 

HR

95% CI

Univariate

Multivariable

Pancreatic tumour origin (pancreatic vs non-pancreatic)

2.3

1.3–4.0

0.004

 

pT stage (pT3 or pT4 vs pT1 or pT2)

2.0

0.9–4.2

0.073

 

Resection margin involvement (R1 vs R0)

1.7

1.0–2.8

0.052

 

Lymph node involvement (N1 vs N0)

3.0

1.6–5.4

< 0.001

0.007

Poor differentiation (yes vs no)

1.6

0.9–2.6

0.094

 

Vessel involvement (yes vs no)

3.1

1.8–5.3

< 0.001

0.035

Perineural infiltration (yes vs no)

2.8

1.4–5.5

0.003

 

Tumour size (continuous, measured in cm)

1.7

1.3–2.1

< 0.001

< 0.001

  1. HR, hazard ratio. HR > 1 indicates increased probability of death
  2. CI, confidence interval