Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma

Table 2 Multivariable Cox regression analysis of histopathologic prognostic factors in periampullary adenocarcinomas (n = 114)

		HR	95% CI	p-value
Histologic type	pancreatobiliary (vs intestinal)	3.1	1.8–5.1	< 0.001
Lymph node involvement	N1 (vs N0)	2.5	1.5–4.4	< 0.001
Vessel involvement	involved (vs not involved)	1.9	1.2–3.1	0.012
Tumour size	diameter (measured in cm)	1.3	1.1–1.5	0.011

HR, hazard ratio. HR > 1 indicates increased probability of death compared to the reference group (for categorical variables) or compared to each increase of one cm in tumour size (continuous variable)
CI, confidence interval

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