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Table 1 Associations between histologic type of differentiation and other histopathologic factors in 114 periampullary adenocarcinomas

From: Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma

  

Differentiation of adenocarcinoma

 
  

intestinal

pancreatobiliary

p-valuea

Tumour origin

ampulla

28

13

< 0.001

 

duodenum

16

0

 
 

distal bile duct

1

16

 
 

pancreas

2

38

 

pT stage

pT1

10

2

< 0.001

 

pT2

20

9

 
 

pT3

8

46

 
 

pT4

9

10

 

Lymph node status

N0

23

26

0.282

 

N1

24

41

 

Resection margin status

R0

40

34

< 0.001

 

R1

7

33

 

Vessel involvement

free

35

36

0.025

 

involved

12

31

 

Perineural infiltration

no

35

17

< 0.001

 

yes

12

50

 

Areas with poorly differentiated tumour

no

39

32

< 0.001

 

yes

8

35

 

Tumour size (maximum tumour diameter)

small (≤ 2.5 cm)

31

35

0.108b

 

large (> 2.5 cm)

16

32

 
  1. aChi-square test, when not otherwise specified
  2. bMann-Whitney test (histologic type of differentiation vs tumour size measured as a continuous variable)