Pathways | Genes in pathway | Probes in reference dataset (n) | Probes in validation dataset (n) | p-value | p-value (FDR adjusted) |
---|---|---|---|---|---|
MAPK 1/3 regulated MMPs | 16 | 17 | 14 | 0.003 | 0.028 |
JNK/MAPK regulated MMPs | 25 | 28 | 19 | 0.003 | 0.028 |
MAPK 1/3 regulated invasion | 35 | 38 | 30 | 0.004 | 0.028 |
MMPs | 9 | 8 | 8 | 0.005 | 0.028 |
HIF1α regulated invasion | 14 | 11 | 11 | 0.011 | 0.048 |
HIF1α regulated angiogenesis | 26 | 21 | 19 | 0.013 | 0.048 |
uPA system | 3 | 3 | 2 | 0.015 | 0.048 |