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Figure 4 | BMC Cancer

Figure 4

From: Diagnostic utility of LunXmRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer

Figure 4

LunX mRNA is the most specific gene marker with high sensitivity for NSCLC cells in pleural fluid. LunX, CK19, CEA, VEGF-C, hnRNP A2/B1 and β-actin mRNA from each pleural fluid sample were detected by real-time RT-PCR, and mRNA copy number was determined by reference to the standard curve, as described in methods. The copy number of each mRNA was further normalized as the ratio to the copy number of β-actin. For each gene marker, when the copy number was less than 100, it could not be detectable as a negative case. All the negative results of each indicated gene were shown as number undetected. The median is marked as "---" in each group. Where the frequency of negative cases is > 50%, the median cannot be shown. The Mann-Whitney U Test was used to compare the gene expression levels between NSCLC and tuberculo pleurisy groups. P < 0.05 (2-tailed test) was considered significant.

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