| |
Number of women
|
Years f/u (Breast ca)
|
Cancers
|
Rate (%/Year)
|
Number of women
|
Years f/u (ovarian ca)
|
Cancers
|
Rate
|
|---|
|
BRCA1 Carriers
|
256
|
1522.33
|
65
|
4.27
|
403
|
2256.13
|
37
|
1.64
|
|
BRCA1 FDR unknown
|
341
|
1988.07
|
13
|
0.65
|
355
|
2049.42
|
6
|
0.29
|
|
BRCA1 Index
|
87
|
399.49
|
37
|
9.3
|
194
|
977.35
|
24
|
2.5
|
|
BRCA1 Carriers less index
|
159
|
1122.33
|
28
|
2.5
|
209
|
1278.78
|
13
|
1.01
|
|
BRCA2 Carriers
|
210
|
1210.41
|
61
|
5.0
|
363
|
2235.14
|
12
|
0.54
|
|
BRCA2 FDR unknown
|
324
|
2096.93
|
12
|
0.57
|
345
|
2187.04
|
4
|
0.19
|
|
BRCA2 Index
|
66
|
285.59
|
36
|
12.6
|
175
|
966.69
|
9
|
0.93
|
|
BRCA2 Carriers less index
|
144
|
924.82
|
25
|
2.7
|
363
|
1268.45
|
3
|
0.24
|
- Censored if affected with relevant cancer prior to date of referral and at RRS, relevant cancer diagnosis, or date of last follow up.
- The index case was used to identify the mutation. Women were censored at time of risk reducing surgery.
