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Table 3 Penetrance for breast and ovarian cancer by age for BRCA1 and BRCA2.

From: Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

Cancer risk to age BRCA1 Breast (se) BRCA2 Breast (se) BRCA1 Ovary (se) BRCA2 Ovary (se)
30 2% 2.5% 0 0
40 16.5%(0.015) 17%(0.019) 3% (0.007) 0
50 48%(0.023) 42%(0.027) 21%(0.02) 4% (0.012)
60 55%(0.027) 63%(0.031) 40%(0.024) 16% (0.03)
70 68% (0.033) 75%(0.033) 60% (0.037) 30% (0.046)
80 79.5% (0.04) 88%(0.037) 65% (0.042) 37% (0.056)
  1. se-standard error