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Figure 3 | BMC Cancer

Figure 3

From: Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

Figure 3

Cumulative risk of breast cancer by age cohort for BRCA1 and BRCA2 combined after exclusion of the index case. Risk to 40 years: Group 1 (birth year <1900; n = 45) 4%; Group 2 (1900–1920; n = 154) 8%; Group 3 (1920–1930; n = 154) 10%; Group 4 (1930–1940; n = 124) 17%; Group 5 (1940–1950; n = 162) 21%; Group 6 (1950–1960; n = 265) 23%; Group 7 (1960+; n = 276) 22%. Log rank (df 6) 153; p = 0.0005.

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BMC Cancer

ISSN: 1471-2407

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