Impairment of intellectual functions after surgery and posterior fossa irradiation in children with ependymoma is related to age and neurologic complications

Table 3 Medical history of the patients and full scale IQ scores at last evaluation.

pt	age	location	hydroc.	shunt	surg.	complications	age at RT	last test	neurology	last IQ
1	13.7 y	FV, obex	yes	no	GTR	no	14 y	17.8 y	normal	84
2	4.3 y	FV, obex	yes	VCS	GTR	no	5.8 y	11.1 y	CS grade 2	83
3	1.5 y	FV, right angle	yes	VCS	GTR	no	2.6 y	4.5 y	normal	85
4	7.7 y	FV	yes	EVD	GTR	no	7.8 y	10.1 y	normal	108
5	13.8 y	FV, obex	yes	EVD	GTR	no	13.8 y	16.2 y	normal	86
6	8.8 y	FV, roof	yes	EVD	STR	no	9.3 y	12.7 y	normal	81
7	14.2 y	FV, angles	no	no	GTR	no	14.4 y	19.7 y	normal	82
8	4.1 y	right angle	no	no	GTR	infection	4.3 y	14.9 y	normal	112
9	10.9 y	FV	yes	VCS	GTR	no	11 y	13.2 y	normal	93
10	3.5 y	FV	yes	no	GTR	no	3.7 y	12.3 y	normal	83
11	8.2 y	right angle	no	no	GTR	no	8.3 y	12 y	paresis VI+VII	93
12	3.7 y	FV, obex	yes	VP	STR	no	3.8 y	10.7 y	CS grade 1	68
13	3.2 y	FV	yes	no	STR	no	3.3 y	17.5 y	normal	104
14	2.5 y	FV	yes	VP	GTR	no	2.7 y	18 y	CS grade 2	70
15	13.5 y	FV	yes	VCS	GTR	no	13.7 y	17.7 y	normal	90
16	0.3 y	FV	yes	no	GTR	no	1.3 y	16.9 y	CS grade 3	75
17	2.5 y	FV, brainstem	yes	no	GTR	no	6.2 y	10.7 y	CS grade 3	71
18	4.5 y	FV	no	no	STR	no	4.6 y	15.8 y	normal	115
19	9.8 y	FV	yes	VP	GTR	no	10 y	15.1 y	ptosis	97
20	2.9 y	FV, right angle	yes	EVD	GTR	subdural eff.	3 y	10.3 y	CS grade 1	65
21	6.8 y	FV to C4	no	no	GTR	no	6.9 y	7.9 y	normal	86
22	8.2 y	FV to C2	no	no	GTR	no	8.3 y	12.8 y	nystagmus	111
23	12.5 y	FV	no	no	GTR	no	12.6 y	14.8 y	normal	108

RT = radiotherapy; IQ = Intellectual Quotient; Hydroc. = hydrocephalus. Presence of hydrocephalus was noted in patients with clinical signs of raised intracranial pressure associated with enlarged lateral ventricles and/or bulging of the third ventricle.
Surg. = extent of surgery; C2–C4 = 2^nd and 4^th cervical vertebra; EVD = external ventricle drainage; VCS = ventriculocisternostomy; VP = ventriculo-peritoneal shunt; GTR = gross total resection; STR = subtotal resection.
CS = cerebellar signs; presence of cerebellar syndrome (Ataxia, Dysmetria, Nystagmus) was graduated as mild, moderate, or severe according to the impact on daily activities by an independent physician unaware of the neuropsychological performance using Riva's rating scale [22].

ISSN: 1471-2407