Table 3 Relationship between the expression of AR, MMPs and TIMPs by each cellular type in breast cancer.
Factor | N | AR score values median (range) | p value |
|---|---|---|---|
MMP-1 | |||
TC (-) vs. (+) | 7/104 | 0(0–70)/80(0–288) | 0.004 |
FC (-) vs. (+) | 14/97 | 2.5(0–225)/80(0–288) | 0.03 |
MIC (-) vs. (+) | 30/81 | 53(0–225)/81(0–288) | n.s. |
MMP-2 | |||
TC (-) vs. (+) | 70/41 | 59.5(0–279)/90(0–288) | n.s. |
FC (-) vs. (+) | 83/28 | 69(0–288)/88(0–270) | n.s. |
MIC (-) vs. (+) | 108/3 | 68.5(0–288)/66(0–132) | n.s. |
MMP-7 | |||
TC (-) vs. (+) | 8/103 | 0(0–156)/80(0–288) | 0.01 |
FC (-) vs. (+) | 27/84 | 68(0–267)/74.5(0–288) | n.s. |
MIC (-) vs. (+) | 50/61 | 66(0–267)/81(0–288) | n.s. |
MMP-9 | |||
TC (-) vs. (+) | 27/84 | 48(0–270)/80.5(0–288) | n.s. |
FC (-) vs. (+) | 93/18 | 68(0–288)/83.5(0–270) | n.s. |
MIC (-) vs. (+) | 98/13 | 80(0–279)/30(0–288) | n.s. |
MMP-11 | |||
TC (-) vs. (+) | 11/100 | 8(0–168)/80(0–288) | 0.03 |
FC (-) vs. (+) | 33/78 | 53(0–264)/81(0–288) | n.s. |
MIC (-) vs. (+) | 72/39 | 68(0–270)/87(0–288) | n.s. |
MMP-13 | |||
TC (-) vs. (+) | 29/82 | 48(0–225)/74.5(0–288) | n.s. |
FC (-) vs. (+) | 54/57 | 56(0–267)/81(0–288) | n.s. |
MIC (-) vs. (+) | 70/41 | 64.5(0–279)/92(0–288) | n.s. |
MMP-14 | |||
TC (-) vs. (+) | 10/101 | 64.5(0–273)/69(0–288) | n.s. |
FC (-) vs. (+) | 21/90 | 92(0–273)/66.5(0–288) | n.s. |
MIC (-) vs. (+) | 50/61 | 64.5(0–273)/81(0–288) | n.s. |
TIMP-1 | |||
TC (-) vs. (+) | 6/105 | 0(0–225)/72(0–288) | n.s. |
FC (-) vs. (+) | 56/55 | 70(0–288)/69(0–273) | n.s. |
MIC (-) vs. (+) | 81/30 | 64(0–279)/96(0–288) | n.s. |
TIMP-2 | |||
TC (-) vs. (+) | 13/98 | 0(0–174)/80(0–288) | 0.01 |
FC (-) vs. (+) | 59/52 | 80(0–270)/63(0–288) | n.s. |
MIC (-) vs. (+) | 63/48 | 80(0–288)/68.5(0–279) | n.s. |
TIMP-3 | |||
TC (-) vs. (+) | 15/96 | 48(0–210)/76(0–288) | n.s. |
FC (-) vs. (+) | 42/69 | 50.5(0–225)/88(0–288) | n.s. |
MIC (-) vs. (+) | 53/58 | 64(0–279)/87(0–288) | n.s. |