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Figure 1 | BMC Cancer

Figure 1

From: Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR

Figure 1

Semi-quantitative evaluation of the expression of VHR phosphatase in a neoplastic and pre-neoplastic cervical lesions. A group of 62 hysterectomy or conization specimens showing the various (pre) neoplastic cervical epithelial lesions (L-SIL (n = 11), H-SIL (n = 18), SCC (n = 12), ADC (n = 12) and AIS (n = 9)) and 35 cases of hysterectomy performed for non-cervical pathologies, from patients under 50 years of age was evaluated for the expression of VHR protein using IHC method on a tissue microarray. The score for VHR staining (staining intensity × staining extent) is presented on the y axis. Each point represents one patient and the average expression level is indicated by a bar. NEx, normal exocervix; NEnd, normal endocervix; L-SIL, low-grade SIL; H-SIL, high-grade SIL; ADC, Adenocarcinoma; AIS, adenocarcinoma in situ. * p < 0.05 and ***p < 0.0001.

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BMC Cancer

ISSN: 1471-2407

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