From: Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas
 | Case (n = 185) | Control (n = 484) | p |
---|---|---|---|
Age (years, mean, se) | 57.3 (0.7) | 55.8 (0.5) | 0.09 |
Race – White (%) | 82 | 78 | 0.28 |
Sex – Male (%) | 59 | 39 | 0.0001 |
Waist/Hip Ratio (mean, se) | 0.93 (0.008) | 0.89 (0.006) | 0.0001 |
Body Mass Index (BMI, kg/m2 (mean, se)) | 28.3 (0.4) | 27.2 (0.3) | 0.04 |
Smoking Status | Â | Â | Â |
   Current (%) | 17 | 10 | 0.09 |
   Former (%) | 37 | 38 |  |
   Never (%) | 46 | 51 |  |
Physical Activity(MET-minutes per day (mean, se)) | 2627 (63) | 2618 (37) | 0.89 |
Family History of CRC2 (% Yes) | 17 | 13 | 0.30 |
Alcohol grams per day (mean, se) | 12.9 (1.7) | 8.2 (0.7) | 0.01 |
Daily Calories (kcal/day (mean, se)) | 1926 (61) | 1866 (34) | 0.37 |
Total Calcium g per day (mean, se) | 896 (37) | 1039 (25) | 0.003 |
Red Meat oz per day (mean, se) | 1.78 (0.11) | 1.45 (0.06) | 0.01 |
Fiber g per day (mean, se) | 20.2 (0.7) | 20.5 (0.4) | 0.75 |
Apoptosis (mean cells/crypt, se) | 3.32 (0.10) | 3.76 (0.06) | 0.0001 |
Tissue IGFBP-3 (mean, se) | 1.13 (0.05) | 1.28 (0.05) | 0.03 |
Plasma IGFBP-3 (ng/ml; mean, se) | 2012 (68) | 2001 (43) | 0.89 |