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Table 3 Summary of EGFR mutation testing by sequencing and HRM

From: High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

Exon

SEQ Positive

HRM Positive

HRM positive only

Sensitivity (%)

Specificity (%)

18

5

23

18

100

91

19

46

67

21

100

88

20

10

23

13

100

93

21

23*

41

18

100

91

  1. * The nine samples containing the SNP c.2508C>T were included.
  2. SEQ: sequencing, HRM: high resolution melting.
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BMC Cancer

ISSN: 1471-2407

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