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Figure 3 | BMC Cancer

Figure 3

From: Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

Figure 3

Effects of TFIIS siRNA on proliferation of lung A549 and pancreatic PL45 cells. A549 and PL45 cell lines were subjected to siRNA directed at TFIIS #1–3, Scrambled siRNA (S-siRNA), or Eg5. Cell proliferation represents the fraction of viable cells compared to cells transfected with vehicle alone (1 = 100% viable cells). Caspase-3/7 activity is also depicted and normalized to cell number represented by MTS values. Total activity was then normalized to activity in cells treated with vehicle alone. TFIIS siRNA #2 nearly perfectly overlays TFIIS siRNA #1 in MCF7 cells and is therefore mostly not visible. Data points represent mean and standard error. The assay was performed 72 hours after initial siRNA transfection.

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