Table 3 Effect of different concentrations of DAC on loss of clonogenicity by L1210 murine lymphoblastic leukemia, or by EMT6 murine mammary tumor cellsa
From: Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer
DAC Concentration ng/ml (μM) | L1210 Loss of clonogenicity (%) | EMT6 Loss of clonogenicity (%) |
|---|---|---|
1 (0.0044) | 25.3 ± 12.4b | - |
10 (0,044) | 41.4 ± 8.8 | 12.3 ± 5.5b |
100 (0.44) | 98.6 ± 1.3 | 69.3 ± 10.3 |
1,000 (4.4) | 100 | 75.0 ± 10.8 |
10,000 (44) | - | 99.2 ± 0.3 |