OAG mediated an inward cationic current in primary hBCE. A) Current-potential relationship in the absence and presenceof OAG (50 μM). The holding potential was -40 mV and 400 ms voltage ramps were applied from -100 mV to +100 mV. B) Time course of the inward whole-cell membrane current activated by OAG (50 μM). C-E) Effects of the common cationic channels inhibitors, 2-APB 50 μM (C), 100 μM (D), and 100 μM La3+ (C, E) on the amplitude of OAG-induced inward current measured at -100 mV.