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Table 3 Correlation of HIF-1α, p53, and VEGF expression with preoperative sVEGF level

From: Clinicopathologic significance of HIF-1α, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer

 

p53

HIF-1α

VEGF

 

-

+

P

-/S

D/V

P

Under

Over

P

HIF-1α

         

   -/S

58

38

0.617*

      

   D/V

12

6

       

VEGF

         

   Under

33

15

0.169*

40

8

0.827*

   

   Over

37

29

 

56

10

    

sVEGF (pg/ml)

         

   Median

103

139

0.705†

147

77

0.438†

153

163

0.146†

   (range)

(8–1076)

(6–642)

 

(6–1076)

(6–761)

 

(8–1076)

(6–761)

 
  1. * by χ2 test, † by Mann-Whitney U test
  2. HIF-1α: hypoxia-inducible factor 1 alpha, VEGF: vascular endothelial growth factor, sVEGF: preoperative serum vascular endothelial growth factor, -/S: negative/superficial pattern, D/V: deep/diffuse/vascular invasion pattern, Under: under-expressed, Over: over-expressed
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BMC Cancer

ISSN: 1471-2407

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