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Table 2 Proteins that showed differential expression after RNAi targeting MBD1

From: Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference

Spot No.

Accession No.

Protein Name

Protein MW

Protein pI

Protein Score

Fold change

429

gi| 5174735

tubulin, beta, 2

49808

4.79

68

↑4.05

896

gi| 5902076

splicing factor, arginine/serine-rich 1 isoform 1

27727.8

10.37

191

↑3.52

384

gi| 1208427

ER-60 protease

56760.8

5.98

140

↑4.09

363

gi| 20070125

prolyl 4-hydroxylase, beta subunit precursor

57058.6

4.76

70

↑4.06

922

gi| 20149675

EF hand domain family, member D2

26680.5

5.15

120

Only in BxPC-3/MBD1-siRNA

218

gi| 14916999

78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5)

72377.5

5.07

249

↓4.02

1023

gi| 6048243

TOLLIP protein

23206.7

5.68

116

Only in BxPC-3/ vector

649

gi| 48257068

HSPA8 protein

64633.1

5.36

95

Only in BxPC-3/ vector

391

gi| 62414289

vimentin

53619.1

5.06

334

↓20.64

1177

gi| 5031851

stathmin 1

17291.9

5.76

90

↓3.48

1264

gi| 14719392

cofilin2

18724.8

7.66

74

Only in BxPC-3/ vector

640

gi| 55958543

heterogeneous nuclear ribonucleoprotein K

33954.7

5.54

74

Only in BxPC-3/ vector

557

gi| 4503519

eukaryotic translation initiation factor 3, subunit 5

37540.1

5.24

131

Only in BxPC-3/ vector

703

gi| 141623

Zinc finger protein ZFP-36

66639.8

8.99

65

Only in BxPC-3/ vector