Skip to main content

Table 5 Composite genotype frequencies for IVS24-9delT, IVS38-8T>C and 5557G>A ATM variants in BRCA1/2 negative breast cancer cases and controls.

From: Association of common ATMvariants with familial breast cancer in a South American population

Composite genotype BC cases (n = 126) Controls (n = 200) p value (a) OR [95%CI]
IVS24-9delT, IVS38-8T>C
T/T, T/T 100 (79.4%) 174 (87.0%) 1.000 1.00
T/(-T), T/T 15 (11.9%) 20 (10.0%) 0.289 1.31 [0.63–2.66]
T/(-T), T/C 11 (8.7%) 6 (3.0%) 0.021 3.19 [1.16–8.89]
IVS38-8T>C, 5557G>A
T/T, G/G 100 (79.4%) 174 (87.0%) 1.000 1.00
T/T, G/A 15 (11.9%) 20 (10.0%) 0.289 1.31 [0.63–2.66]
T/C, G/A 11 (8.7%) 6 (3.0%) 0.021 3.19 [1.16–8.89]
IVS24-9delT, 5557G>A
T/T, G/G 100 (79.4%) 174 (87.0%) 1.000 1.00
T/(-T), G/A 26 (20.6%) 26 (13.0%) 0.048 1.74 [0.96–3.16]
IVS24-9delT, IVS38-8T>C, 5557G>A
T/T, T/T, G/G 100 (79.4%) 174 (87.0%) 1.000 1.00
T/(-T), T/T, G/A 15 (11.9%) 20 (10.0%) 0.289 1.31 [0.63–2.66]
T(/-T), T/C, G/A 11 (8.7%) 6 (3.0%) 0.021 3.19 [1.16–8.89]
  1. BC: breast cancer.
  2. (a) Fisher exact test.