Sequencing of chemo- and radiotherapy | ||||||
---|---|---|---|---|---|---|
all patients n = 212 | sequential n = 86 | sandwich n = 70 | simultaneous n = 56 | pa (two-sided) | ||
Age n (%) | age ≤ 50 | 41 (19.3) | 14 (16.3) | 15 (21.4) | 12 (21.4) | 0.7 |
age > 50 | 171 (80.7) | 72 (83.7) | 55 (78.6) | 44 (78.6) | ||
histological type n (%) | ductal-invasiv | 158 (74.5) | 65 (79.3) | 48 (68.6) | 45 (80.4) | 0.7 |
ductal-lobular | 35 (16.5) | 14 (17.1) | 14 20) | 7 (12.5) | ||
other | 19 (9) | 7 (8.1) | 8 (11.4) | 4 (7.1) | ||
pT n (%) | pT1/2 | 123 (58) | 53 (61.6) | 40 (57.1) | 30 (53.6) | 0.4 |
pT3/4 | 89 (42) | 33 (38.4) | 30 (42.9) | 26 (46.4) | ||
pN n (%) | pN0 | 48 (22.6) | 12 (14) | 14 (20) | 22 (39.3) | 0.004 |
pN1 | 35 (16.5) | 18 (20.9) | 8 (11.4) | 9 (16.1) | ||
pN2-3 | 129 (60.9) | 56 (65.1) | 48 (68.6) | 25 (44.6) | ||
LVI n (%) | yes | 77 (36.3) | 22 (25.6) | 40 (57.1) | 15 (26.8) | < 0.0001 |
no | 135 (63.7) | 64 (74.4) | 30 (42.9) | 41 (73.2) | ||
G n (%) | G1 | 5 (2.4) | 3 (3.5) | 1 (1.4) | 1 (1.8) | 0.2 |
G2 | 89 (42) | 36 (41.9) | 23 (32.9) | 30 (53.6) | ||
G3 | 118 (55.7) | 47 (54.7) | 46 (65.7) | 25 (44.6) | ||
ECS n (%) | yes | 110 (51.9) | 50 (58.1) | 41 (58.6) | 19 (33.9) | 0.007 |
no | 102 (48.1) | 36 (41.9) | 29 (41.4) | 37 (66.1) | ||
Receptor (ER and/or PR) n (%) | positive | 158 (74.5) | 66 (76.7) | 53 (75.7) | 39 (69.6) | 0.6 |
negative | 54 (25.5) | 20 (23.3) | 17 (24.3) | 17 (30.4) | ||
R n (%) | R0 | 197 (92.9) | 81 (94.2) | 64 (91.4) | 52 (92.9) | 0.9 |
R+ | 15 (7.1) | 5 (5.8) | 6 (8.6) | 4 (7.1) | ||
V n (%) | yes | 194 (91.5) | 81 (94.2) | 60 (85.7) | 53 (94.6) | 0.1 |
no | 18 (8.5) | 5 (5.8) | 10 (14.3) | 3 (5.4) | ||
RT region n (%) parasternal fields (in 28.3% created) not separately considered | THW + SIA | 148 (69.8) | 62 (72.1) | 56 (80) | 30 (53.6) | 0.01 |
THW only | 17 (8) | 6 (7) | 6 (8.6) | 5 (8.9) | ||
SIA only | 47 (22.2) | 18 (20.9) | 8 (11.4) | 21 (37.5) |