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Table 1 Distribution of categorical parameters in patients with sequential, sandwich or simultaneous chemo- and radiotherapy (a done by Pearson x2-test)

From: Sequencing chemotherapy and radiotherapy in locoregional advanced breast cancer patients after mastectomy – a retrospective analysis

    Sequencing of chemo- and radiotherapy
   all patients n = 212 sequential n = 86 sandwich n = 70 simultaneous n = 56 pa (two-sided)
Age n (%) age ≤ 50 41 (19.3) 14 (16.3) 15 (21.4) 12 (21.4) 0.7
  age > 50 171 (80.7) 72 (83.7) 55 (78.6) 44 (78.6)  
histological type n (%) ductal-invasiv 158 (74.5) 65 (79.3) 48 (68.6) 45 (80.4) 0.7
  ductal-lobular 35 (16.5) 14 (17.1) 14 20) 7 (12.5)  
  other 19 (9) 7 (8.1) 8 (11.4) 4 (7.1)  
pT n (%) pT1/2 123 (58) 53 (61.6) 40 (57.1) 30 (53.6) 0.4
  pT3/4 89 (42) 33 (38.4) 30 (42.9) 26 (46.4)  
pN n (%) pN0 48 (22.6) 12 (14) 14 (20) 22 (39.3) 0.004
  pN1 35 (16.5) 18 (20.9) 8 (11.4) 9 (16.1)  
  pN2-3 129 (60.9) 56 (65.1) 48 (68.6) 25 (44.6)  
LVI n (%) yes 77 (36.3) 22 (25.6) 40 (57.1) 15 (26.8) < 0.0001
  no 135 (63.7) 64 (74.4) 30 (42.9) 41 (73.2)  
G n (%) G1 5 (2.4) 3 (3.5) 1 (1.4) 1 (1.8) 0.2
  G2 89 (42) 36 (41.9) 23 (32.9) 30 (53.6)  
  G3 118 (55.7) 47 (54.7) 46 (65.7) 25 (44.6)  
ECS n (%) yes 110 (51.9) 50 (58.1) 41 (58.6) 19 (33.9) 0.007
  no 102 (48.1) 36 (41.9) 29 (41.4) 37 (66.1)  
Receptor (ER and/or PR) n (%) positive 158 (74.5) 66 (76.7) 53 (75.7) 39 (69.6) 0.6
  negative 54 (25.5) 20 (23.3) 17 (24.3) 17 (30.4)  
R n (%) R0 197 (92.9) 81 (94.2) 64 (91.4) 52 (92.9) 0.9
  R+ 15 (7.1) 5 (5.8) 6 (8.6) 4 (7.1)  
V n (%) yes 194 (91.5) 81 (94.2) 60 (85.7) 53 (94.6) 0.1
  no 18 (8.5) 5 (5.8) 10 (14.3) 3 (5.4)  
RT region n (%) parasternal fields (in 28.3% created) not separately considered THW + SIA 148 (69.8) 62 (72.1) 56 (80) 30 (53.6) 0.01
  THW only 17 (8) 6 (7) 6 (8.6) 5 (8.9)  
  SIA only 47 (22.2) 18 (20.9) 8 (11.4) 21 (37.5)