Skip to main content

Table 4 Association of MDM2 SNP309 with lung cancer within NSCLC cases

From: Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

genotype OR 95% CI p-value
all: NSCLC cases (n = 434) vs. controls (n = 1295)
TG vs. GG 1.1§ 0.7–1.6 0.828
TT vs. GG 1.0§ 0.7–1.5 0.841
men: NSCLC cases (n = 280) vs. controls (n = 815)
TG vs. GG 1.2§§ 0.7–2.9 0.422
TT vs. GG 1.2§§ 0.7–2.9 0.515
women: NSCLC cases (n = 154) vs. controls (n = 479)
TG vs. GG 0.8§§ 0.4–1.6 0.471
TT vs. GG 0.7§§ 0.4–4.0 0.323
gender difference in genotypic ORs 0.237
  1. § conditional to age/gender-strata (6 groups) and adjusted for smoking exposure§§ conditional to age-strata (3 groups) and adjusted for smoking exposure and gender