Table 2 Combined analysis of TNFα -1031T/C and NOD2 3020insC in consecutively collected CRC cases compared to matched control subjects.
From: Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk
NOD2 WT/WT | NOD2 WT/insC + insC/insC | |||||
|---|---|---|---|---|---|---|
Gene | Controls | CRC | OR (95%CI) | Controls | CRC | OR (95% CI) |
TNFα T/T | 384 | 390 | 1.00 | 27 | 41 | 1.50 (0.90–2.49) |
TNFα T/C | 150 | 142 | 0.93 (0.71–1.22) | 20 | 19 | 0.94 (0.49–1.79) |
TNFα C/C | 24 | 12 | 0.49 (0.24–1.00) | 2 | 3 | 1.48 (0.25–8.97) |