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Table 1 Percentage of QDs injected quantity detected in ALN by spectrofluorometry after chemical extraction.

From: Quantum dots in axillary lymph node mapping: Biodistribution study in healthy mice

5 min

15 min

30 min

60 min

24 h

0.47 ± 0.21% **

0.27 ± 0.10% **

1.00 ± 0.47% **

2.42 ± 0.57% **

1.24 ± 0.34% **

  1. 20 pmol were injected subcutaneously in the anterior paw of nude mice. After sacrifice at 5 min, 15 min, 30 min, 60 min and 24 h after injection, ALN was removed, solubilized and the fluorescence of the solution was measured and is expressed as a percentage of the injected doze. Values were expressed by mean ± SEM, values marked with asterisk were significantly different from control (P < 0.01). QDs: Quantum Dots; ALN: Axillary Lymph Node