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Table 1 Percentage of QDs injected quantity detected in ALN by spectrofluorometry after chemical extraction.

From: Quantum dots in axillary lymph node mapping: Biodistribution study in healthy mice

5 min 15 min 30 min 60 min 24 h
0.47 ± 0.21% ** 0.27 ± 0.10% ** 1.00 ± 0.47% ** 2.42 ± 0.57% ** 1.24 ± 0.34% **
  1. 20 pmol were injected subcutaneously in the anterior paw of nude mice. After sacrifice at 5 min, 15 min, 30 min, 60 min and 24 h after injection, ALN was removed, solubilized and the fluorescence of the solution was measured and is expressed as a percentage of the injected doze. Values were expressed by mean ± SEM, values marked with asterisk were significantly different from control (P < 0.01). QDs: Quantum Dots; ALN: Axillary Lymph Node