From: Prospective single-arm study of 72 Gy hyperfractionated radiation therapy and combination chemotherapy for anaplastic astrocytomas
Total failure
14/44 (32%)
Failure inside field
7/14 (50%)
Failure outside field
10/14 (71%) (CSF dissemination: 9, contralateral brain: 1)
Severe late toxicity
Brain necrosis
1 (2%)