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Table 5 Aminoacid repeat length variations in ATBF1

From: ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: Absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism

Exon nr AA position AA Repeat Nature – frequency In tumors* Allele loss In normals In BC patients**
2 487 Glu 15 bp del – 1 4/116 (3.4%) 1 wt 1/172 (0.6%) 7/541 (1.3%)
    12 bp ins – 11   2 variants
1 no loss
  
9 1741 Gln 3 bp del – 1 2/110 (1.8%) 2 wt 5/162 (3.1%) 11/539 (2.0%)
    6 bp del – 4     
    3 bp ins – 4     
    6 bp ins – 10     
10 3202 Gln 21 bp del – 8 1/98 (1%) 1 variant 1/146 (0.7%) 6/530 (1.1%)
10 3380 Gln 3 bp del – 5 6/115 (5.2%) 2 wt 11/148 (7.4%) 27/351 (7.7%)
    6 bp del – 15   4 Variants   
    3 bp ins – 24     
  1. * All normal DNAs of these patients show the same variant.
  2. ** Tested on normal DNA from peripheral blood cells