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Table 1 In vivo pharmacokinetic parameters of 5-FU and 5-FU/PEG-PBLG nanoparticles
From:
Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles
t
1/2
(h)
C
max
(μg/L)
T
max
(h)
V
d
(L)
AUC(μg · h/L)
5-FU
0.088
17047.3
0
0.069
6263.7
5-FU/PEG-PBLG
33.3
4563.5
1.25
0.114
5794.7
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