Table 1 In vivo pharmacokinetic parameters of 5-FU and 5-FU/PEG-PBLG nanoparticles
From: Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles
| t1/2(h) | Cmax (μg/L) | Tmax(h) | Vd(L) | AUC(μg · h/L) | |
|---|---|---|---|---|---|
| 5-FU | 0.088 | 17047.3 | 0 | 0.069 | 6263.7 |
| 5-FU/PEG-PBLG | 33.3 | 4563.5 | 1.25 | 0.114 | 5794.7 |