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Table 3 Association of EGFR gene alterations with clinicopathological parameters

From: Epidermal growth factor receptor structural alterations in gastric cancer

Clinicopathological parameters EGFR status
  Amplification/mutation (n = 6) Normal (n = 24) Total (n = 30) p value
Sex (F/M) 1/5 10/14 11/19 0.2557
Age (SD) 62.3 ± 14,1 56.3 ± 16.8 57.5 ± 16.2 0.4271
Tumour localization     0.8548
   Proximal 3 11 14  
   Distal 3 13 16  
Size (SD) 11.6 ± 9.8 5.8 ± 2.0 6.9 ± 5.0 *0.0094
Lauren's classification     0.1261
   Intestinal 1 12 13  
   Diffuse 5 9 14  
   Atypical 0 3 3  
Wall penetration     0.4642
   Early (T1) 0 2 2  
   Advanced (T2-T4) 6 22 28  
Vascular Invasion     0.7125
   Absent (N0) 3 14 17  
   Present (N = 1) 3 10 13  
Lymph node metastasis     0.1921
   Absent 1 11 12  
   Present 5 13 18  
Staging     0.3845
   I 1 7 8  
   II 0 5 5  
   III 5 11 16  
   IV 0 1 1