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Figure 1 | BMC Cancer

Figure 1

From: Activation of Akt is increased in the dysplasia-carcinoma sequence in Barrett's oesophagus and contributes to increased proliferation and inhibition of apoptosis: a histopathological and functional study

Figure 1

Immunohistochemistry of activated (phospho-) and total Akt in Barrett's oesophagus. a: Phospho-Akt localisation in non-dysplastic Barrett's oesophagus showing staining in gland crypts but not surface epithelium (original magnification × 20). b: Phospho-Akt localisation in high-grade dysplasia in Barrett's oesophagus with showing staining throughout the epithelium reaching the luminal surface (original magnification × 20). c: Phospho-Akt expression in oesophageal adenocarcinoma showing staining throughout the epithelium reaching the luminal surface (original magnification × 20). d: Total Akt expression in non-dysplastic Barrett's oesophagus showing considerable staining in epithelial cells in all layers (original magnification × 10).

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