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Table 2 The effects of aspirin or/and PEITC on the expressions of PCNA and COX-2

From: Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate

Group

Number of rat

% Cells Positive for PCNA

Mean (SD)

Scores for COX-2

Mean (SD)

A.aspirin

10

12.05(8.81)

2.08(0.72)â—†

B.PEITC

10

10.92(11.55)

2.34(0.95)

C.asprin + PEITC

10

4.25(5.27)◆◆

1.60(0.73)◆◆

D.Positive control

8

24.48(9.14) **

3.13(0.88) **

E.Negative control

9

1.17(0.56)

0.67(0.35)

  1. *p < 0.05 when compared with negative control group.
  2. **p < 0.01 when compared with negative control group.
  3. â—† p < 0.05 when compared with positive control group.
  4. ◆◆p < 0.01 when compared with positive control group.