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Table 2 The effects of aspirin or/and PEITC on the expressions of PCNA and COX-2

From: Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate

Group Number of rat % Cells Positive for PCNA
Mean (SD)
Scores for COX-2
Mean (SD)
A.aspirin 10 12.05(8.81) 2.08(0.72)
B.PEITC 10 10.92(11.55) 2.34(0.95)
C.asprin + PEITC 10 4.25(5.27) 1.60(0.73)
D.Positive control 8 24.48(9.14) ** 3.13(0.88) **
E.Negative control 9 1.17(0.56) 0.67(0.35)
  1. *p < 0.05 when compared with negative control group.
  2. **p < 0.01 when compared with negative control group.
  3. p < 0.05 when compared with positive control group.
  4. p < 0.01 when compared with positive control group.