TY - JOUR AU - Warnat, Patrick AU - Oberthuer, André AU - Fischer, Matthias AU - Westermann, Frank AU - Eils, Roland AU - Brors, Benedikt PY - 2007 DA - 2007/05/25 TI - Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes JO - BMC Cancer SP - 89 VL - 7 IS - 1 AB - Neuroblastoma patients show heterogeneous clinical courses ranging from life-threatening progression to spontaneous regression. Recently, gene expression profiles of neuroblastoma tumours were associated with clinically different phenotypes. However, such data is still rare for important patient subgroups, such as patients with MYCN non-amplified advanced stage disease. Prediction of the individual course of disease and optimal therapy selection in this cohort is challenging. Additional research effort is needed to describe the patterns of gene expression in this cohort and to identify reliable prognostic markers for this subset of patients. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-7-89 DO - 10.1186/1471-2407-7-89 ID - Warnat2007 ER -