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Table 3 The down-regulated genes by less than 1/3-fold in the AOM/DSS group at wk 5

From: Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate

Gene name (gene symbol)

Average fold of change (AOM/DSS vs. untreated)

Solute carrier family 10, member 2 (Slc10a2)

0.12

Rho GTPase activating protein 20 (Arhgap20)

0.12

Cytochrome P450, family 2, subfamily d, polypeptide 26 (Cyp2d26)

0.13

Aldehyde dehydrogenase family 1, subfamily A1 (Aldh1a1)

0.14

Dipeptidase 1 (renal) (Dpep1)

0.15

UDP-glucuronosyltransferase 8 (Ugt8)

0.15

Dehydrogenase/reductase (SDR family) member 8 (Dhrs8)

0.15

Solute carrier family 3, member 1 (Slc3a1)

0.16

Paired-like homeodomain transcription factor 2 (Pitx2)

0.19

Glycoprotein galactosyltransferase alpha 1, 3 (Ggta1)

0.19

N-acetylglutamate synthase (Nags)

0.19

Adrenergic receptor, alpha 2a (Adra2a)

0.19

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (Hmgcs2)

0.2

Cytochrome P450, family 4, subfamily f, polypeptide 16 (Cyp4f16)

0.2

Glucosaminyl (N-acetyl) transferase 3, mucin type (Gcnt3)

0.2

Glutamyl aminopeptidase (Enpep)

0.2

Homeo box B5 (Hoxb5)

0.22

Caudal type homeo box 2 (Cdx2)

0.22

Fatty acid binding protein 2, intestinal (Fabp2)

0.22

Glutamic pyruvic transaminase 1, soluble (Gpt1)

0.22

Mitogen activated protein kinase 10 (Mapk10)

0.23

Meprin 1 alpha (Mep1a)

0.23

UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase (Galgt1)

0.23

CD36 antigen (Cd36)

0.25

Mercaptopyruvate sulfurtransferase (Mpst)

0.25

FK506 binding protein 5 (Fkbp5)

0.27

Acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) (Acaa2)

0.27

Histocompatibility 2, class II antigen E alpha (H2-Ea)

0.27

RAB37, member of RAS oncogene family (Rab37)

0.27

BRAF35/HDAC2 complex (Bhc80)

0.29

Protein tyrosine phosphatase, receptor type, R (Ptprr)

0.29

N-acylsphingosine amidohydrolase (alkaline ceramidase) 3 (Asah3)

0.29

Pyruvate dehydrogenase kinase, isoenzyme 4 (Pdk4)

0.31

Nuclear receptor subfamily 5, group A, member 2 (Nr5a2)

0.31

RIKEN cDNA 9030612M13 gene (9030612M13Rik)

0.31

Mitogen activated protein kinase kinase kinase 2 (Map3k2)

0.31

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2)

0.31

Vanin 1 (Vnn1)

0.31

ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a)

0.31

Kinesin family member C3 (Kifc3)

0.31

3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2)

0.33

Cytochrome P450, family 2, subfamily c, polypeptide 55 (Cyp2c55)

0.33

Ring finger protein 130 (Rnf130)

0.33

Phosphate cytidylyltransferase 1, choline, alpha isoform (Pcyt1a)

0.33

Potassium channel, subfamily K, member 5 (Kcnk5)

0.33

Solute carrier family 9 (sodium/hydrogen exchanger), member 2 (Slc9a2)

0.33

Solute carrier family 20, member 1 (Slc20a1)

0.33

Synaptotagmin-like 4 (Sytl4)

0.33

Regulator of G-protein signaling 13 (Rgs13)

0.33

Diaphanous homolog 1 (Drosophila) (Diap1)

0.33

Fibrinogen-like protein 2 (Fgl2)

0.33

Epidermal growth factor (Egf)

0.33