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Table 1 Primary information of selected SNPs of the XPC gene

From: Sequence variations in DNA repair gene XPCis associated with lung cancer risk in a Chinese population: a case-control study

Gene [accession no.] and locus NCBI rs no. location AAa change Base change MAFb of cases MAFb of controls MAFb in EGPc MAFb in HapMapd % genotyped
XPC [NCBI: AY131066] 3p25.1 rs3731055 000603, close to 5'UTR   G > A 0.25 0.27 0.07 --- 96.6
  rs2607775 000947, close to 5'UTR   C > G 0.04 0.04 0.35 --- 98.3
  rs3729587 012413, intron 5   C > G 0.11 0.11 0.35 --- 92.5
  rs2228000 021151, exon 9 A499V C > T 0.33 0.32 0.24 0.30 98.2
  rs2228001 033512, exon 16 K939Q A > C 0.38 0.36 0.34 0.38 98.2
  1. aAA: amino acid.
  2. bMAF: Minor allele frequencies.
  3. cEGP: US environmental Genome Project SNP database.
  4. dHapMap: For Chinese included in the International HapMap Project.