Table 1 Frequency of methylation in each marker according to 18q LOH status in MSI-L/MSS colorectal cancers
18q LOH status | Total N | No. of tumors with methylation in: | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | CACNA1G | CDKN2A (p16) | CRABP1 | IGF2 | MLH1 | NEUROG1 | RUNX3 | SOCS1 |
LOH(+) | 236 | 23 (9.7%) | 55 (23%) | 44 (19%) | 28 (12%) | 4 (1.7%) | 44 (19%) | 15 (6.4%) | 15 (6.4%) |
LOH(-) | 138 | 26 (19%) | 38 (28%) | 47 (34%) | 30 (22%) | 3 (2.2%) | 41 (30%) | 23 (17%) | 14 (10%) |