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Table 3 Nucleotide differences in the FOXO1A 3'-UTR.

From: Aberrant over-expression of a forkhead family member, FOXO1A, in a brain tumor cell line

DNA source

Position of Base Change Relative to Transcriptional Start Site

Base Change Observed

Published SNP NCBI – SNP Database Build 126

Promoter Region Clones

-832

A/G

No

PCR Product

2464 to 2474

single base insertion (A)

Yes dbSNP: 11406284

PCR Product and Clone

2476 to 2486

single base deletion (A)

No

PCR Product and Clone

2986 to 2994

single base deletion (A)

Yes dbSNP: 3841231

PCR Product

4338

G/C

No

 

4356

C/T

No

  1. Overlapping genomic or RT-PCR fragments were sequenced and compared to the canonical FOXO1A sequence (Genbank accession no. NM_002015).