|
Gene SNP
| |
Cases
|
Controls
|
OR**
|
95% CI
|
P-trend
|
|---|
|
SHBG
| | | | | | |
|
rs1799941
|
AA
|
144
|
278
|
1.00
| | |
|
-67G>A
|
AG
|
118
|
287
|
0.79
|
0.59 – 1.07
| |
|
5'UTR
|
GG
|
23
|
57
|
0.79
|
0.46 – 1.33
|
0.14
|
|
rs6257
|
TT
|
242
|
520
|
1.00
| | |
|
IVS1-17T>C
|
TC
|
41
|
91
|
0.97
|
0.65 – 1.44
| |
| |
CC
|
2
|
2
|
2.13
|
0.29 – 15.3
|
0.75
|
|
rs6259
|
AA
|
254
|
547
|
1.00
| | |
|
Ex8+6G>A
|
AG
|
30
|
72
|
0.89
|
0.57 – 1.40
| |
|
D356N
|
GG
|
1
|
4
|
0.51
|
0.06 – 4.65
|
0.72
|
|
rs727428
|
CC
|
119
|
264
|
1.00
| | |
|
1121 bp 3' of STP T>C
|
CT
|
121
|
278
|
0.96
|
0.71 – 1.30
| |
| |
TT
|
45
|
81
|
1.25
|
0.81 – 1.91
|
0.48
|
|
rs1641544
|
CC
|
261
|
580
|
1.00
| | |
|
31959 bp 3' of STP T>C
|
CT
|
22
|
38
|
1.34
|
0.77 – 2.33
|
0.30
|
| |
TT
|
1
|
0
| | | |
|
ATP1B2
| | | | | | |
|
rs1641537 ***
|
CC
|
215
|
486
|
1.00
| | |
|
-9115T>C
|
CT
|
66
|
125
|
1.21
|
0.86 – 1.71
| |
| |
TT
|
3
|
8
|
0.90
|
0.23 – 3.46
|
0.36
|
|
rs1624085
|
CC
|
116
|
246
|
1.00
| | |
|
Ex2G>C
|
CG
|
120
|
292
|
0.86
|
0.64 – 1.18
| |
| |
GG
|
49
|
84
|
1.25
|
0.82 – 1.90
|
0.60
|
|
rs1641512
|
GG
|
193
|
401
|
1.00
| | |
|
Ex7+414G>A
|
GA
|
80
|
195
|
0.86
|
0.63 – 1.17
| |
| |
AA
|
12
|
27
|
0.94
|
0.46 – 1.90
|
0.42
|
- * Differences between the total number of cases and controls and frequencies shown in the table are due to missing genotype data.
- ** Adjusted for age and city.
- *** Highly correlated with ATP1B1 rs1641536 (18852T>C) and rs1641535 (-8703T>c), r2 > 0.98, not shown in table to avoid redundancy.
