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Table 1 Personal and tumor characteristics of 264 ovarian cancer cases and 625 controls in the Polish Ovarian Cancer Study.

From: Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study

 

Cases* N = 264

Controls* N = 625

P**

Study site, N %

   Warsaw

177

67%

423

68%

0.85

   Lodz

87

33%

202

32%

 

Age, mean SD in years

56.3

10.8

56.1

10.8

0.83

No. of full-term births, N %

   Nulliparous

50

19%

79

13%

<0.0001

   1

101

38%

176

28%

 

   2

94

36%

273

44%

 

   ≥ 3

19

7%

97

16%

 

Number of ovulatory cycles, mean SD

410.9

71.1

398.1

81.3

0.03

Use of oral contraceptive, N %

   Never

245

94%

556

90%

0.08

   Ever

16

6%

60

10%

 

Currently having menstrual periods, N %

   No

182

71%

401

66%

0.40

   Yes

75

29%

203

34%

 

   Unclear

7

3%

20

3%

 

Use of oral hormone replacement therapy among post-menopausal women

   Never

146

81%

325

82%

 

   Ever

35

19%

70

18%

0.15

Family history of breast or ovarian cancer in first-degree relatives, N %

   No

210

80%

553

88%

0.001

   Breast cancer only

26

10%

24

4%

 

   Ovarian cancer only

26

10%

40

6%

 

   Both

2

1%

8

1%

 

Tumor Characteristics

Histology, N (%)

   Serous

118

45%

   

   Mucinous

26

10%

   

   Endometrioid

58

22%

   

   Clear cell

14

5%

   

   Mixed

18

7%

   

   Others or unclassified

30

11%

   

Stage, N % distant

110

62%

   

   Not staged or missing

86

    

Grade of differentiation, N %

   Well

21

13%

   

   Moderate

59

35%

   

   Poor

88

52%

   

   Missing

96

    
  1. * Differences between the total number of cases and controls and frequencies shown in the table are due to missing data.
  2. ** P values for categorical variables are based on chi squared tests, and on t-tests for continuous variables.