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Table 4 Clinical course of the gefitinib-responders who achieved PD, underwent various treatments except for chemotherapy, and resumed gefitinib

From: Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer

No.

Treatment after gefitinib failure

Response after gefitinib resumption

Time to re-progression (month)

1

RT to bone mets, Pleurodesis,

SD

2.9

2

RT to brain mets,

SD

8.9

3

RT to bone mets,

SD

19.1+

4

RT to bone and brain mets, Pleurodesis,

SD

6.5

  1. "Resumption" of gefitinib indicates restarting gefitinib within 4 weeks after temporary cessation of gefitinib. RT, radiotherapy; mets, metastasis; Time to re-progression, time to progression from the date of resuming gefitinib; +, still continuing the response at the last date of follow-up
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BMC Cancer

ISSN: 1471-2407

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