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Table 4 Percentage of tumours from subgroups 1 to 12 that show the best scores for the respective molecular signatures as defined by Chi2 analysis

From: A new molecular breast cancer subclass defined from a large scale real-time quantitative RT-PCR study

Subgroups defined by hierarchical clustering

 

1

2

3

4

5

6

7

8

9

10

11

12

1

62

7

0

6

0

0

0

6

0

0

8

0

2

15

86

4

25

14

0

9

29

0

0

17

29

3

23

14

96

41

0

5

0

24

0

0

33

0

5

0

0

0

9

71

21

0

6

0

0

17

14

6

8

0

0

0

14

58

5

12

0

0

0

29

7

0

0

0

16

14

21

86

24

9

13

17

14

9

0

0

0

3

0

0

0

12

82

0

8

0

10

0

0

0

0

0

0

0

0

9

88

0

0

12

0

0

0

0

0

0

0

0

0

0

0

43

  1. Columns represent the different tumour subgroups as defined by Eisen's hierarchical clustering. Rows are related to the distinct molecular signatures determined by Chi2. The percentage of tumours from Eisen's subgroups that exhibited proper molecular signatures are highlighted in bold. The sum of the % from each column may be higher than 100% as some tumours could exhibit extra signatures. As 41% of tumours from subgroup 4 exhibited the molecular signature that specified subgroup 3, tumours from subgroups 3 and 4 were assembled for the rest of the study.