Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases

BMC Cancer

Table 2 Immunohistochemical results of 21 SCC cases

Case No	Pathology	CK	EMA	NSE	Syn	CgA	CD56	S-100	TTF-1
1	SCC	++	+++	+++	+++	++	+++	-	+++
2	SCC	+++	++	+	++	-	+	-	-
3	SCC	++	+++	++	+++	+	+++	-	++
4	SCC	+++	++	++	++	++	++	++	+++
5	SCC	++	+++	-	+	-	+++		-
6	SCC	++	++	+	+++	++	++	-	+++
7	SCC	+++	++	+	++	+	+++	+	++
8	SCC	+++	++	+++	++	-	+++	-	++
9	SCC	-	-	+++	+++	++	+++	++	+++
	SqCC	+++	++	-	-	-	-	-	-
10	SCC	-	+	+	+++	+++	-	-	++
11	SCC	-	-	-	++	-	++	-	-
12	SCC	-	-	-	++	-	-	-	+
13	SCC	-	-	++	+++	++	+++	-	-
14	SCC	++	-	+	+++	++	++	-	+++
15	SCC	+	++	-	++	++	+++	-	++
16	SCC	-	-	-	++	-	-	-	++
17	SCC	++	+++	++	+++	+	+++	+	-
18	SCC	-	++	-	-	++	-	-	+++
19	SCC	++	++	-	++	-	+++	-	-
20	SCC	-	-	+	+++	-	++	-	++
21	SCC	-	-	-	+++	+++	-	-	++
	SqCC	+++	-	-	-	-	-	-	-
Total positive cases (%)		12(57.1)	13(61.9)	13(61.9)	20(95.2)	13(61.9)	16(76.2)	4(19.0)	15(71.4)

SCC, small cell carcinoma; SqCC, squamous cell carcinoma. +, less than 10% of the tumor cells were positive; ++, 10%–50% of the tumor cells were positive; +++, more than 50% the tumor cells were positive; -, negative labeling.

ISSN: 1471-2407