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Table 3 DSS by patient characteristics with Cox and Log normal analysis1

From: Disease-specific survival for limited-stage small-cell lung cancer affected by statistical method of assessment

Group A – Low risk characteristics:

(complete resection, hemoglobin: ≥ 100 for both sexes, no lymph node involvement, no SVC obstruction)

 

Estimated disease-specific survival probabilities (in per cent, with 95% confidence intervals, CI) at 1, 3, and 5 years by different methods

Methods:

1

3

5

Cox

94 (87,97)

65 (38,82)

58 (31,78)

Log-normal survival analysis

98 (87,99.9)

82 (46,97)

64 (26,92)

Group B – Intermediate risk #1: (incomplete or no resection, hemoglobin: ≥ 100 for both sexes, no lymph node involvement, no SVC obstruction)

 

Estimated disease-specific survival probabilities (in per cent, with 95% confidence intervals, CI) at 1, 3, and 5 years by different methods

Methods:

1

3

5

Cox

91 (85,95)

52 (33,68)

45 (26,62)

Log-normal survival analysis

95 (77,99)

67 (32,91)

45 (16,78)

Group C – Intermediate risk #2: (incomplete or no resection, hemoglobin: < 100 for both sexes, no lymph node involvement, no SVC obstruction)

 

Estimated disease-specific survival probabilities (in per cent, with 95% confidence intervals, CI) at 1, 3, and 5 years by different methods

Methods:

1

3

5

Cox

78 (31,95)

16 (0,67)

11 (0,62)

Log-normal survival analysis

84 (55,97)

42 (14,76)

23 (5,56)

Group D – High risk characteristics: (no resection, hemoglobin: < 100 for both sexes, lymph node involvement, SVC obstruction)

 

Estimated disease-specific survival probabilities (in per cent, with 95% confidence intervals, CI) at 1, 3, and 5 years by different methods

Methods:

1

3

5

Cox

66 (19,90)

5 (0,48)

3 (0, 41)

Log-normal survival analysis

67 (27,93)

22 (4,40)

9 (1,38)

  1. 1 The subgroups contained a total of 8 patients and 4 events.