Table 2 Adjusted Mean Percent Densities (%) by Genotype*

All

AA

863

285

27.8

Val/Val

688

229

28.6

AC

750

254

29.7

Val/Met

780

257

29.1

CC

109

36

32.9

Met/Met

254

89

29.4

P (trend) ^‡

-

-

0.11

P (trend) ^‡

-

-

0.70

Controls

AA

315

124

22.4

Val/Val

235

95

23.6

AC

253

108

25.4

Val/Met

264

108

24.6

CC

46

18

31.3

Met/Met

115

47

25.1

P (trend) ^‡

-

-

0.045

P (trend) ^‡

-

-

0.61

Cases

AA

548

161

31.1

Val/Val

453

134

31.4

AC

497

146

31.4

Val/Met

516

149

31.5

CC

63

18

32.0

Met/Met

139

42

30.3

P (trend) ^‡

-

-

0.86

P (trend) ^‡

-

-

0.84

Premenopausal

AA

154

71

35.2

Val/Val

125

62

35.7

AC

129

60

36.1

Val/Met

124

55

37.8

CC

9

4

44.8

Met/Met

43

18

30.8

P (trend) ^‡

-

-

0.38

P (trend) ^‡

-

-

0.60

Postmenopausal

AA

652

189

25.9

Val/Val

523

150

26.5

AC

566

170

27.4

Val/Met

596

174

27.0

CC

92

27

31.4

Met/Met

191

62

27.6

P (trend) ^‡

-

-

0.14

P (trend) ^‡

-

-

0.67

Postmenopausal

AA

258

113

20.5

Val/Val

180

90

21.6

No HRT use

AC

186

98

23.1

Val/Met

225

104

21.7

CC

21

11

29.6

Met/Met

60

28

24.4

P (trend) ^‡

-

-

0.08

P (trend) ^‡

-

-

0.57

Postmenopausal

AA

228

97

29.2

Val/Val

176

81

29.3

HRT use

AC

192

88

30.4

Val/Met

192

79

30.8

CC

28

14

31.7

Met/Met

80

39

29.2

P (trend) ^‡

-

-

0.48

P (trend) ^‡

-

-

0.88

BMI < 25

AA

504

157

34.2

Val/Val

412

135

35.4

AC

485

163

37.1

Val/Met

505

154

36.1

CC

71

21

43.6

Met/Met

143

52

37.8

P (trend) ^‡

-

0.046

P (trend) ^‡

-

-

0.53

BMI >= 25

AA

359

128

19.2

Val/Val

276

94

19.0

AC

265

81

19.2

Val/Met

275

103

19.4

CC

38

15

18.6

Met/Met

111

37

18.9

P (trend) ^‡

-

0.92

P (trend) ^‡

-

-

0.96