Skip to main content

Table 6 Comparison of sensitivity and specificity of the αFP levels for the diagnosis of hepatocellular carcinoma (HCC) of several studies

From: The progressive elevation of alpha fetoprotein for the diagnosis of hepatocellular carcinoma in patients with liver cirrhosis

Authors αFP 10–16 (ng/mL) αFP 20 (ng/mL) αFP 100 (ng/mL) αFP 200 (ng/mL) αFP 300 (ng/mL) αFP 400 (ng/mL)
  S (%) E (%) S (%) E (%) S (%) E (%) S (%) E (%) S (%) E (%) S (%) E (%)
Oka et al 1994    39 76 13 97       
Pateron et al 1994 50 86    21 93       
Peng et al 1999    65 87    45 100     
Tong et al 2001    41 94         
Trevisani et al 2001 62.4 89.4 60 90.6 31.2 98.8 22 99 22.4 99.4 17.1 99.4
Gebo et al 2002*    60         0–64 100
Nguyen et al 2002 78.4 61.1 63 80 41.4 97.3 32 100     
Gupta et al 2003*    41–65 80–94         
Farinati et al 2006    54         18  
Arrieta 2007+ 63.2 95.9 60.6 95.9 47.2 99 36.3 100 22.8 100 20.2 100
  1. S = sensitivity, E = specificity.
  2. * Literature review
  3. + Present study