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Table 5 Positive Predictive Value (PPV) and Negative Predictive Value (NPV) for the diagnosis of HCC with αFP values ≥200, αFP values ≥ 400 ng/mL and with the progressive elevation of αFP of 5 ng/mL with a prevalence of 5 and 10%.

From: The progressive elevation of alpha fetoprotein for the diagnosis of hepatocellular carcinoma in patients with liver cirrhosis

αFP HCC Prevalence (%) PPV (%) NPV (%)
≥200 ng/ml 10 97.58 93.4
  5 95.03 96.7
≥400 ng/ml 10 95.7 91.86
  5 91.4 95.97
Elevation ≥7 ng/ml/month 10 98.7 96.92
  5 97.4 98.52