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Table 5 Positive Predictive Value (PPV) and Negative Predictive Value (NPV) for the diagnosis of HCC with αFP values ≥200, αFP values ≥ 400 ng/mL and with the progressive elevation of αFP of 5 ng/mL with a prevalence of 5 and 10%.

From: The progressive elevation of alpha fetoprotein for the diagnosis of hepatocellular carcinoma in patients with liver cirrhosis

αFP

HCC Prevalence (%)

PPV (%)

NPV (%)

≥200 ng/ml

10

97.58

93.4

 

5

95.03

96.7

≥400 ng/ml

10

95.7

91.86

 

5

91.4

95.97

Elevation ≥7 ng/ml/month

10

98.7

96.92

 

5

97.4

98.52